Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 264
interventional 136
Observational 118
Registry 10

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Behavioral 25
Other 23
Drug 19
Device 17
Procedure 13
Drug|placebo 11
Diagnostic Test 7
Dietary Supplement 5
Biological 3
Drug|Other 3
Other|Procedure 3
Drug|Procedure 2
Behavioral|Other 1
Behavioral|Procedure 1
Combination Product 1
Device|Procedure 1
Dietary Supplement|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 49
Canada 18
France 8
NA 8
Brazil 5
Belgium 4
China 4
Germany 4
Korea, Republic of 3
Sweden 3
Egypt 2
Netherlands 2
Russian Federation 2
Taiwan 2
United States|Canada 2
Australia 1
Australia|Austria|Belgium|Canada|France|Germany|Hungary|Israel|Italy|Netherlands|Romania|Spain|Turkey|United Kingdom 1
Austria|Germany 1
Austria|Switzerland 1
Brazil|China|Russian Federation 1
Denmark 1
Denmark|Sweden 1
Finland|Sweden 1
Germany|United Kingdom 1
Indonesia 1
Norway 1
Portugal 1
Switzerland 1
Turkey 1
United States|Argentina|Belgium|Brazil|Canada|China|Denmark|Egypt|Finland|France|Germany|Hong Kong|Hungary|India|Israel|Italy|Korea, Republic of|Malaysia|Mexico|Netherlands|Norway|Poland|Portugal|Russian Federation|Singapore|South Africa|Spain|Sweden|Taiwan|Thailand|United Kingdom 1
United States|Austria|Belgium|Bulgaria|Canada|Czech Republic|Denmark|France|Germany|Hungary|Israel|Lebanon|Poland|Russian Federation|Spain|Sweden|United Kingdom 1
United States|Austria|Canada|Spain 1
United States|Belgium|Canada|France|Germany|Italy 1
United States|Brazil|France|Germany|Hungary|India|Italy|Malaysia|Mexico|Poland|Portugal|Russian Federation|Spain|Taiwan|United Kingdom 1
United States|Canada|Mexico 1

Sites per Study

Site_count Study_Count
1 102
2 5
3 4
4 3
5 3
6 1
7 3
8 2
9 1
12 3
13 1
15 1
16 1
17 1
20 1
29 1
31 1
43 1
153 1

Phase

Phase Study_Count
N/A 89
Phase 3 14
Phase 2 13
Phase 1 6
Phase 4 6
Phase 1/Phase 2 4
Phase 2/Phase 3 3
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 35
2 77
3 11
NA 13

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 2 5.0000 4.0 17.00 14.0000 21.0 49.0000 10.00000
1st Qu. 2 34.5000 10.5 20.75 40.0000 38.0 100.0000 54.00000
Median 2 64.0000 18.0 24.00 72.0000 55.0 195.0000 83.00000
Mean 2 600.4483 26.0 75.75 166.8462 106.0 255.1538 85.66667
3rd Qu. 2 143.5000 27.0 79.00 102.0000 148.5 236.0000 115.00000
Max. 2 34704.0000 78.0 238.00 1236.0000 242.0 906.0000 168.00000

Trial Group Type

group_type Group_Count
Experimental 107
Active Comparator 39
No Intervention 35
Placebo Comparator 20
Other 18
NA 13
Sham Comparator 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 85
Single Group Assignment 40
Crossover Assignment 4
NA 3
Factorial Assignment 2
Sequential Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 67
Prevention 17
Supportive Care 17
Other 15
Diagnostic 12
Health Services Research 4
NA 4

Observational Studies

Studies by Country

Country Study_Count
United States 40
NA 13
France 12
China 8
Belgium 7
Norway 5
Switzerland 4
Germany 3
Korea, Republic of 3
Canada 2
Denmark 2
Egypt 2
Israel 2
United Kingdom 2
Brazil 1
Hong Kong 1
Italy 1
Russian Federation 1
Singapore 1
Slovenia 1
Spain 1
Sweden 1
United States|Argentina|Australia|Belgium|Canada|France|India|Italy|Japan|Malta|Netherlands|Norway|Sweden|Switzerland|Taiwan 1
United States|Australia 1
United States|Belarus|Ukraine 1
United States|Nigeria|Thailand 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 101
2 8
3 3
5 1
7 1
9 1
12 1
13 1
24 1

Enrollment Metrics

Measure Observational
Min 3.00
1st Qu 51.50
Median 148.00
Mean 98581.29
3rd Qu 475.00
Max 9999999.00

Observation Model

observational_model Study_Count
Cohort 62
Case-Only 20
Case-Control 11
NA 11
Case Control 6
Case-Crossover 2
Family-Based 2
Other 2
Case Control, Natural History 1
Ecologic or Community 1

Time Perspective

time_perspective Study_Count
Prospective 76
Cross-Sectional 16
Retrospective 16
NA 9
Other 1

Registries

Studies by Country

Country Study_Count
Canada 1
China 1
Egypt 1
France 1
Netherlands 1
Norway 1
Switzerland 1
United States 1
United States|Australia|Canada|China|India|Korea, Republic of|Nepal|Russian Federation|Saudi Arabia|Ukraine 1
United States|Austria 1

Sites per Study

Site_count Study_Count
1 7
3 1
6 1
18 1

Enrollment Metrics

Measure Registries
Min 29.0
1st Qu 165.0
Median 440.0
Mean 1547.7
3rd Qu 2527.0
Max 5000.0

Registry Model

observational_model Study_Count
Cohort 7
Case-Only 3

Time Perspective

time_perspective Study_Count
Prospective 6
Cross-Sectional 3
Other 1

Follow-up

target_duration Study_Count
2 Years 3
24 Months 2
1 Day 1
1 Year 1
20 Years 1
4 Days 1
4 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03311438 Oral Health Intervention Program for Children With Congenital Heart Defects https://ClinicalTrials.gov/show/NCT03311438 Completed University of Bergen 2016-10-03
NCT03303248 Evaluation of Web-based Transition Education to Enhance Transition Readiness https://ClinicalTrials.gov/show/NCT03303248 Recruiting University of Michigan 2020-06-01
NCT03297658 Electro-acupuncture (EA) in Children Undergoing Procedures for Congenital Heart Defects. https://ClinicalTrials.gov/show/NCT03297658 Recruiting West Virginia University 2020-09-30
NCT03215628 Quantification of Cerebral Perfusion by Contrast-enhanced Ultrasound During Neonatal Heart Surgery https://ClinicalTrials.gov/show/NCT03215628 Recruiting University of Erlangen-Nürnberg Medical School 2020-06-30
NCT03110861 Pulsta® Transcatheter Pulmonary Valve Korean Multicenter Study https://ClinicalTrials.gov/show/NCT03110861 Active, not recruiting Taewoong Medical Co., Ltd. 2019-11-06
NCT03078218 Health-economic Impact of Pulse Oximetry Systematic Screening of Critical Congenital Heart Disease in Asymptomatic Newborns https://ClinicalTrials.gov/show/NCT03078218 Recruiting University Hospital, Bordeaux 2020-03-01
NCT03050112 Long-term Quality of Life of Patients With a Congenital Heart Disease, Treated by Surgery in Adulthood at the Brugmann Hospital. https://ClinicalTrials.gov/show/NCT03050112 Completed Brugmann University Hospital 2017-06-01
NCT03049540 Effect of Phosphodiesterase-5 Inhibition With Tadalafil on SystEmic Right VEntricular Size and Function https://ClinicalTrials.gov/show/NCT03049540 Active, not recruiting University Hospital Inselspital, Berne 2021-05-31
NCT03035552 CTICU Pacifier Activated Music Player and Mother’s Voice https://ClinicalTrials.gov/show/NCT03035552 Enrolling by invitation Nationwide Children’s Hospital 2019-01-31
NCT03023644 Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study https://ClinicalTrials.gov/show/NCT03023644 Active, not recruiting Boston Children’s Hospital 2019-12-01
NCT03022708 Xeltis Bioabsorbable Pulmonary Valved Conduit Early Feasibility Study https://ClinicalTrials.gov/show/NCT03022708 Active, not recruiting Xeltis 2019-12-31
NCT03005626 Transition From Adolescents to Adulthood for Patients With Congenital Heart Diseases https://ClinicalTrials.gov/show/NCT03005626 Recruiting University Hospital, Montpellier 2020-02-29
NCT02990754 Fearless Physical Activity: Getting and Keeping Ontarians With Congenital Heart Disease Active https://ClinicalTrials.gov/show/NCT02990754 Completed Children’s Hospital of Eastern Ontario 2018-03-31
NCT02987387 COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve Dysfunction https://ClinicalTrials.gov/show/NCT02987387 Recruiting Edwards Lifesciences 2022-07-31
NCT02860702 Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology https://ClinicalTrials.gov/show/NCT02860702 Recruiting The University of Texas Health Science Center at San Antonio 2020-12-31
NCT02831790 The Fontan Education Study: A Randomized Control Trial https://ClinicalTrials.gov/show/NCT02831790 Completed University of Alberta 2018-07-31
NCT02806245 Biventricular Pacing in Children After Surgery for Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02806245 Completed The Hospital for Sick Children 2013-12-31
NCT02766998 Preserved Umbilical Vein Use as Autologous Shunt Conduits in Neonatal Cardiac Surgery https://ClinicalTrials.gov/show/NCT02766998 Recruiting Boston Children’s Hospital 2021-01-31
NCT02759263 Improving Neurodevelopment in Adolescents With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02759263 Completed Boston Children’s Hospital 2018-09-30
NCT02752191 Feraheme As An MRI Contrast Agent For Pediatric Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02752191 Recruiting University of California, Los Angeles 2021-04-30
NCT02744677 COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction https://ClinicalTrials.gov/show/NCT02744677 Recruiting Edwards Lifesciences 2023-01-31
NCT02737579 XFM: (X-ray Fused With MRI) Guided Cardiac Catheterization https://ClinicalTrials.gov/show/NCT02737579 Active, not recruiting Children’s National Research Institute 2023-08-31
NCT02710825 Osteopathy and Children With Congenital Heart Disease Surgery https://ClinicalTrials.gov/show/NCT02710825 Completed Hôpital Necker-Enfants Malades 2017-02-23
NCT02675361 Effectiveness of a Transition Program for Adolescents With Congenital Heart Disease in the Transition to Adulthood https://ClinicalTrials.gov/show/NCT02675361 Active, not recruiting Göteborg University 2021-12-31
NCT02673697 Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement https://ClinicalTrials.gov/show/NCT02673697 Active, not recruiting LivaNova 2019-10-31
NCT02647541 Preoperative Nutritional Intervention and Outcomes of Children Submitted to Heart Surgery for Congenital Heart Diseases https://ClinicalTrials.gov/show/NCT02647541 Completed University of Sao Paulo 2013-02-28
NCT02644824 Biventricular Pacing in Children With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02644824 Completed The Hospital for Sick Children 2018-04-30
NCT02622152 Right Lateral Positioning of Postoperative Pediatric Cardiac Surgery https://ClinicalTrials.gov/show/NCT02622152 Recruiting Assiut University 2018-09-30
NCT02615262 Intraoperative Dexamethasone in Pediatric Cardiac Surgery https://ClinicalTrials.gov/show/NCT02615262 Completed Meshalkin Research Institute of Pathology of Circulation 2018-11-30
NCT02537392 Multi-micronutrient Supplementation During Peri-conception and Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02537392 Completed Health Science Center of Xi’an Jiaotong University 2019-12-31
NCT02564796 Erythropoietin to Prevent Unnecessary Transfusions In Patients With Cyanotic Congenital Heart Disease - A Prospective Control Trial https://ClinicalTrials.gov/show/NCT02564796 Recruiting University of California, San Diego 2021-02-28
NCT02561975 Adaptation of Alveolar-capillary Diffusion at Effort of Subjects Suffering From Complex Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02561975 Completed University Hospital, Montpellier 2016-12-31
NCT02555319 A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV) https://ClinicalTrials.gov/show/NCT02555319 Active, not recruiting Seoul National University Hospital 2017-04-30
NCT02549625 Phase I Safety and Feasibility Study of Intracoronary Delivery of Autologous Bone Marrow Derived Mononuclear Cells https://ClinicalTrials.gov/show/NCT02549625 Active, not recruiting ReGen Theranostics, Inc. 2020-11-30
NCT02493634 Post-market Clinical Follow-up Study With Magnetic Resonance Imaging Conditional Guide Wire https://ClinicalTrials.gov/show/NCT02493634 Completed Nano4Imaging GmbH 2017-01-18
NCT02462434 Impact of Early Intervention on Maternal Stress in Mothers of Fetuses Diagnosed With Single Ventricle Physiology https://ClinicalTrials.gov/show/NCT02462434 Completed University of Michigan 2015-10-12
NCT02389491 Effect of a High Density Formula on Growth and Safety in Congenital Heart Disease Infants https://ClinicalTrials.gov/show/NCT02389491 Completed Children’s Hospital of Fudan University 2015-10-31
NCT02377700 Safety and Performance of a Vascular Patch in Pediatric Patients Undergoing Bidirectional Cava-pulmonary Anastomosis https://ClinicalTrials.gov/show/NCT02377700 Active, not recruiting Xeltis 2015-09-30
NCT02377674 Safety and Performance of the COR-VG-001 Conduit in Pediatric Patients for Extracardiac Total Cavopulmonary Connection https://ClinicalTrials.gov/show/NCT02377674 Active, not recruiting Xeltis 2015-09-30
NCT02374892 The CHAPTER III Study of Young Adolescents https://ClinicalTrials.gov/show/NCT02374892 Completed University of Alberta 2018-12-31
NCT02347189 Melody PB1016 Surveillance Study https://ClinicalTrials.gov/show/NCT02347189 Completed Medtronic Cardiovascular 2016-11-30
NCT02320669 Phase 3 Triiodothyronine Supplementation for Infants After Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT02320669 Recruiting Seattle Children’s Hospital 2019-10-31
NCT02240147 Start-to-Sport - Home-based Exercise for Adolescents and Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02240147 Completed KU Leuven 2018-09-30
NCT02232399 Is Levosimendan Superior to Milrinone Regarding Acute Kidney Injury After Cardiac Surgery for Congenital Heart Disease? https://ClinicalTrials.gov/show/NCT02232399 Completed Göteborg University 2017-04-25
NCT02157597 NIRS Guidance Trail in Children’s Heart Surgery https://ClinicalTrials.gov/show/NCT02157597 Completed Children’s Hospital Medical Center, Cincinnati 2016-01-31
NCT02133573 Randomized Trial of Maternal Progesterone Therapy https://ClinicalTrials.gov/show/NCT02133573 Active, not recruiting Children’s Hospital of Philadelphia 2021-12-31
NCT01292551 Study of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology. https://ClinicalTrials.gov/show/NCT01292551 Completed Rigshospitalet, Denmark 2013-03-31
NCT01286480 Congenital Heart Adolescents: Program of Transition Evaluation Research https://ClinicalTrials.gov/show/NCT01286480 Completed University of Alberta 2013-11-30
NCT01280227 Supporting Patient Provider Communication in Paediatric Care https://ClinicalTrials.gov/show/NCT01280227 Completed Oslo University Hospital 2010-10-31
NCT04453761 Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT04453761 Active, not recruiting National Cardiovascular Center Harapan Kita Hospital Indonesia 2021-12-01
NCT04452201 Parent Communication for Feeding an Infant With a Heart Defect https://ClinicalTrials.gov/show/NCT04452201 Completed University of Wisconsin, Madison 2019-05-02
NCT01881893 Feasibility Study of the Adult Congenital Heart Disease-Coping and Resilience (ACHD-CARE) Trial https://ClinicalTrials.gov/show/NCT01881893 Completed University Health Network, Toronto 2015-12-31
NCT01838447 Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level https://ClinicalTrials.gov/show/NCT01838447 Completed Children’s Hospital of Eastern Ontario 2015-12-31
NCT01835392 Neuroprotective Effects of Remote Ischemic Preconditioning (RIPC) During Infant Cardiac Surgery https://ClinicalTrials.gov/show/NCT01835392 Completed Nemours Children’s Clinic 2018-01-31
NCT01822769 Cardiopulmonary Rehabilitation for Adolescents and Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01822769 Completed Boston Children’s Hospital 2016-08-31
NCT01810978 Synbiotics in Infants With Cyanotic Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01810978 Completed Dr. Sami Ulus Children’s Hospital 2013-04-30
NCT01785498 Healthy Lifestyles for Children With Complex Heart Problems https://ClinicalTrials.gov/show/NCT01785498 Completed Children’s Hospital of Eastern Ontario 2013-09-30
NCT01671566 Interval Training in Adults With Congenital Heart Disease a Randomized Trial https://ClinicalTrials.gov/show/NCT01671566 Completed Umeå University 2016-03-31
NCT01662037 Bosentan Therapy in Children With Functional Single Ventricle https://ClinicalTrials.gov/show/NCT01662037 Completed Shanghai Jiao Tong University School of Medicine 2011-09-30
NCT01548950 Drug Therapy and Surgery in Congenital Heart Disease With Pulmonary Hypertension https://ClinicalTrials.gov/show/NCT01548950 Completed University of Sao Paulo General Hospital 2014-01-31
NCT03944837 Acute Maternal Hyperoxygenation in CHD https://ClinicalTrials.gov/show/NCT03944837 Recruiting The Hospital for Sick Children 2022-12-31
NCT01484886 Restrictive Versus Liberal Transfusion Protocol in Infants Undergoing Cardiac Surgery https://ClinicalTrials.gov/show/NCT01484886 Completed University of Rochester 2014-09-30
NCT01475357 Intestinal Function in Neonates With Complex Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01475357 Completed Medical University of South Carolina 2014-03-31
NCT01426542 Preventing Brain Injury in Infants With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01426542 Completed University of California, Davis 2017-07-28
NCT01397110 Respiratory and Physical Therapy in Patients With Associated Pulmonary Arterial Hypertension (APAH) With Congenital Heart Defects https://ClinicalTrials.gov/show/NCT01397110 Recruiting Heidelberg University 2025-12-31
NCT01330433 Effects of CoSeal on Bleeding & Adhesions in Pediatric Heart Surgery https://ClinicalTrials.gov/show/NCT01330433 Completed Loma Linda University 2015-08-31
NCT04264650 Effectiveness of an mHealth Intervention for Youth With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT04264650 Completed National Yang Ming University 2018-02-28
NCT04262037 A Comparative Study of Three Modes of Ventilation During CPB in Pediatrics With Pulmonary Hypertension Undergoing Congenital Heart Surgeries https://ClinicalTrials.gov/show/NCT04262037 Recruiting Cairo University 2020-07-31
NCT04217421 Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT04217421 Recruiting UMC Utrecht 2021-06-01
NCT04208893 Exercise Training Strategies for Children With Repaired Tetralogy of Fallot https://ClinicalTrials.gov/show/NCT04208893 Recruiting The Hospital for Sick Children 2021-08-31
NCT04194502 Coronary Artery Assessement by TEE in Congenital Heart Disease https://ClinicalTrials.gov/show/NCT04194502 Completed The Hospital for Sick Children 2018-06-18
NCT04152330 Proposal for Parental Guidance and Early Stimulation in Children With Congenital Heart Disease: Randomized Trial https://ClinicalTrials.gov/show/NCT04152330 Recruiting Instituto de Cardiologia do Rio Grande do Sul 2020-03-30
NCT04090827 The Transitioning Rural Adolescents to Adult Care Study https://ClinicalTrials.gov/show/NCT04090827 Recruiting University of Alberta 2023-12-31
NCT04076501 Effect of Short-term Oxygen During CPET in GUCH https://ClinicalTrials.gov/show/NCT04076501 Recruiting University of Zurich 2020-12-31
NCT04056416 Physical Activity Promotion in Children and Adolescents With Single Ventricle Physiology (MedBike) https://ClinicalTrials.gov/show/NCT04056416 Enrolling by invitation University of Alberta 2021-12-31
NCT04056104 Improving Critical Congenital Heart Disease Screening With Addition of Perfusion Measurements https://ClinicalTrials.gov/show/NCT04056104 Enrolling by invitation University of California, Davis 2021-12-31
NCT04055883 Clinical Study to Evaluate Efficacy and Safety of DA-1229 in Patients With CAVD https://ClinicalTrials.gov/show/NCT04055883 Recruiting Dong-A ST Co., Ltd. 2022-12-31
NCT03999320 Sophrology and Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03999320 Recruiting University Hospital, Montpellier 2022-08-01
NCT03928002 4DFlow Magnetic Resonance Imaging in Patients With Pulmonary Hypertension Associated With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03928002 Recruiting Centre Chirurgical Marie Lannelongue 2020-04-01
NCT03925584 The Use of Music for Neonates Post-Cardiac Surgery https://ClinicalTrials.gov/show/NCT03925584 Recruiting Boston Children’s Hospital 2019-12-31
NCT03913520 Outcome of Patients With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03913520 Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2021-04-30
NCT03891160 Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment https://ClinicalTrials.gov/show/NCT03891160 Recruiting Columbia University 2025-07-31
NCT03757312 A Pilot Study of Optic Nerve Ultrasound Following Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT03757312 Enrolling by invitation Nationwide Children’s Hospital 2020-12-31
NCT03724006 Impact of Psychoeducation in Quality of Life of Parents With Children With Congenital Heart Defects https://ClinicalTrials.gov/show/NCT03724006 Recruiting Universidade do Porto 2021-02-28
NCT03690518 Rehabilitation of Adolescents and Young Adults With Congenital Heart Diseases https://ClinicalTrials.gov/show/NCT03690518 Recruiting University Hospital, Montpellier 2021-07-27
NCT03667703 Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03667703 Recruiting Boston Children’s Hospital 2020-06-30
NCT03630796 Effect of Sevoflurane in Postoperative Troponin I Levels in Children Undergoing Congenital Heart Defects Surgery https://ClinicalTrials.gov/show/NCT03630796 Recruiting Instituto do Coracao 2019-12-31
NCT03611374 Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study https://ClinicalTrials.gov/show/NCT03611374 Recruiting Stanford University 2020-06-06
NCT03488797 Web-based Motor Intervention to Increase Health Related Physical Fitness in Children With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03488797 Active, not recruiting Deutsches Herzzentrum Muenchen 2019-09-20
NCT03482141 Clinical Utility of Prenatal Whole Exome Sequencing https://ClinicalTrials.gov/show/NCT03482141 Recruiting University of California, San Francisco 2021-04-30
NCT03479957 Remotely Monitored and Coached Cardiac Rehabilitation Northern Sweden https://ClinicalTrials.gov/show/NCT03479957 Recruiting Umeå University 2020-12-31
NCT03471936 Right Ventricular Diastolic Function in Chronic Adverse RV Loading And Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03471936 Recruiting University of Leipzig 2019-12-01
NCT03431480 Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery https://ClinicalTrials.gov/show/NCT03431480 Recruiting Murdoch Childrens Research Institute 2020-02-28
NCT03417999 Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03417999 Active, not recruiting Children’s Hospital of Philadelphia 2021-01-31
NCT01208792 Auto-immunity and Pulmonary Arterial Hypertension https://ClinicalTrials.gov/show/NCT01208792 Completed Assistance Publique - Hôpitaux de Paris 2014-07-15
NCT01189981 Effect of eHealth Encouragements to Intensive Exercise in Adolescents With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01189981 Completed Rigshospitalet, Denmark 2014-05-31
NCT01069510 Spironolactone in Adult Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01069510 Completed Oregon Health and Science University 2016-06-30
NCT01034007 A Pilot Study Investigating the Clinical Use of Tissue Engineered Vascular Grafts in Congenital Heart Surgery https://ClinicalTrials.gov/show/NCT01034007 Completed Nationwide Children’s Hospital 2017-12-26
NCT01032876 Cerebral Perfusion During Neonatal Cardiac Surgery https://ClinicalTrials.gov/show/NCT01032876 Completed UMC Utrecht 2012-06-30
NCT01018472 Probiotics in Infants With Cyanotic Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01018472 Completed University of California, Davis 2011-02-28
NCT00974688 Optimizing Health Among Children With Congenital Heart Defects https://ClinicalTrials.gov/show/NCT00974688 Completed The Hospital for Sick Children 2011-12-31
NCT00968565 Study Using Citrate to Replace Heparin in Babies Requiring Extracorporeal Membrane Oxygenation (ECMO) https://ClinicalTrials.gov/show/NCT00968565 Completed Vanderbilt University 2015-06-30
NCT00945529 The Effects of Inhaled Nitric Oxide After Fontan Operation https://ClinicalTrials.gov/show/NCT00945529 Completed Nemours Children’s Clinic 2011-12-31
NCT00930800 Exercise Training in Children With Congenital Heart Defect https://ClinicalTrials.gov/show/NCT00930800 Completed National Taiwan University Hospital 2008-06-30
NCT00881686 Myocardial Protection With Adenosine Preconditioning https://ClinicalTrials.gov/show/NCT00881686 Completed Xijing Hospital 2008-12-31
NCT00868101 The Effect of Remote Ischemic Preconditioning Applied in Children the Day Before Open Heart Surgery https://ClinicalTrials.gov/show/NCT00868101 Completed University of Sao Paulo 2009-11-30
NCT04416230 Post-Op Massage in Infants With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT04416230 Completed Ohio State University 2013-08-03
NCT03366597 The Research of the Effect of Sevoflurane on Brain-protection of Cardiac Surgery in Infants. https://ClinicalTrials.gov/show/NCT03366597 Recruiting Beijing Anzhen Hospital 2019-12-31
NCT00833703 Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt Palliation https://ClinicalTrials.gov/show/NCT00833703 Completed Sanofi 2010-07-31
NCT03435354 Enhanced Physical Activity Support in Congenital Heart Disease Clinical Care https://ClinicalTrials.gov/show/NCT03435354 Enrolling by invitation Children’s Hospital of Eastern Ontario 2020-03-31
NCT01570933 Feasibility Study Over the NAVA Mode in Noninvasive Ventilation After Cardiac Surgery in Infants. https://ClinicalTrials.gov/show/NCT01570933 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2013-12-31
NCT04437069 Improving Patient and Family Health Using Family-Centered Outcomes and Shared Decision-Making https://ClinicalTrials.gov/show/NCT04437069 Recruiting University of Utah 2022-06-30
NCT00740870 Melody Transcatheter Pulmonary Valve (TPV) Study: Post Approval Study of the Original Investigational Device Exemption (IDE) Cohort https://ClinicalTrials.gov/show/NCT00740870 Active, not recruiting Medtronic Cardiovascular 2015-05-31
NCT00585013 Inhaled NO as an Anti-inflammatory and Anti-reperfusion Agent in Infants and Children Undergoing Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT00585013 Completed Washington University School of Medicine 2011-06-30
NCT00538785 A Study to Evaluate MEDI-524 In Children With Hemodynamically Significant Congenital Heart Disease https://ClinicalTrials.gov/show/NCT00538785 Completed MedImmune LLC 2008-06-30
NCT00450684 Cardiac Resynchronization Therapy in Congenital Heart Defects https://ClinicalTrials.gov/show/NCT00450684 Completed Competence Network for Congenital Heart Defects 2012-02-29
NCT00443599 SPECS: Safe Pediatric Euglycemia in Cardiac Surgery https://ClinicalTrials.gov/show/NCT00443599 Completed Boston Children’s Hospital 2012-06-30
NCT00396877 Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation https://ClinicalTrials.gov/show/NCT00396877 Completed Sanofi 2010-02-28
NCT00371891 Ontario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS) https://ClinicalTrials.gov/show/NCT00371891 Completed St. Joseph’s Healthcare Hamilton 2009-06-30
NCT00363363 Physical Activity in Fontan Patients https://ClinicalTrials.gov/show/NCT00363363 Completed The Hospital for Sick Children 2008-06-30
NCT00335244 Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery https://ClinicalTrials.gov/show/NCT00335244 Completed Asklepion Pharmaceuticals, LLC 2009-12-31
NCT00308230 Pilot Study of B-Type Natrieutic Peptide (BNP) Levels in Patients With Congenital Heart Disease(BNP) https://ClinicalTrials.gov/show/NCT00308230 Completed Emory University 2004-03-31
NCT00226369 Cylexin for Reduction of Reperfusion Injury in Infant Heart Surgery https://ClinicalTrials.gov/show/NCT00226369 Completed Boston Children’s Hospital NA
NCT00201214 Citrulline for Children Undergoing Cardiopulmonary Bypass Surgery https://ClinicalTrials.gov/show/NCT00201214 Completed Vanderbilt University 2006-01-31
NCT00199771 Hypertonic Saline Dextran in Pediatric Cardiac Surgery https://ClinicalTrials.gov/show/NCT00199771 Completed Oslo University Hospital 2004-12-31
NCT00000494 Management of Patent Ductus in Premature Infants https://ClinicalTrials.gov/show/NCT00000494 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00115934 Comparison of Two Types of Shunts in Infants With Single Ventricle Defect Undergoing Staged Reconstruction–Pediatric Heart Network https://ClinicalTrials.gov/show/NCT00115934 Completed HealthCore-NERI 2009-09-30
NCT00115375 Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO) https://ClinicalTrials.gov/show/NCT00115375 Completed Sanofi NA
NCT00113087 Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle–Pediatric Heart Network https://ClinicalTrials.gov/show/NCT00113087 Completed National Heart, Lung, and Blood Institute (NHLBI) 2008-07-31
NCT00112424 Trial of Cardiac Magnetic Resonance Imaging (MRI) Versus Cardiac Catheterization Prior to Glenn Operation https://ClinicalTrials.gov/show/NCT00112424 Completed Boston Children’s Hospital 2006-06-30
NCT00027417 Study of Triostat in Infants During Heart Surgery https://ClinicalTrials.gov/show/NCT00027417 Completed Seattle Children’s Hospital 2007-08-31
NCT00004828 Liothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedure https://ClinicalTrials.gov/show/NCT00004828 Completed FDA Office of Orphan Products Development NA
NCT00001460 Evaluation and Treatment of Heart Disease in Patients Not Participating in Research https://ClinicalTrials.gov/show/NCT00001460 Completed National Institutes of Health Clinical Center (CC) NA
NCT00000470 Infant Heart Surgery: Central Nervous System Sequelae of Circulatory Arrest https://ClinicalTrials.gov/show/NCT00000470 Completed Boston Children’s Hospital 1992-02-29
NCT00006186 Autologous Fresh Whole Blood and Coagulation Following Cardiopulmonary Bypass in Infants https://ClinicalTrials.gov/show/NCT00006186 Completed National Center for Research Resources (NCRR) NA
NCT00006183 Comparison of Hematocrit Levels in Infant Heart Surgery https://ClinicalTrials.gov/show/NCT00006183 Completed National Heart, Lung, and Blood Institute (NHLBI) 2005-07-31

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03360370 Neurodevelopmental Disorders in Children With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03360370 Completed University Hospital, Lille 2018-06-06
NCT03356574 Long-term Survival After Single-ventricle Palliation https://ClinicalTrials.gov/show/NCT03356574 Active, not recruiting Karolinska University Hospital 2018-12-31
NCT03255850 The Impact of Congenital Heart Disease on the Psychological Well Being and Quality of Life in the Hong Kong Chinese Adolescents https://ClinicalTrials.gov/show/NCT03255850 Completed The University of Hong Kong 2018-08-31
NCT03248830 Non-invasive Hemoglobin Monitoring in Congenital Heart Diseased Children https://ClinicalTrials.gov/show/NCT03248830 Completed Cairo University 2019-08-01
NCT03170024 Health Literacy in Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03170024 Active, not recruiting Stanford University 2019-12-30
NCT03154112 Validation of a Novel Oxygen Consumption Measurement Technique in Neonates https://ClinicalTrials.gov/show/NCT03154112 Completed Boston Children’s Hospital 2019-01-01
NCT03144258 Evaluation of the Microcirculation During the Corrective Surgery of Congenital Heart Defects in Children https://ClinicalTrials.gov/show/NCT03144258 Completed National Institute of Cardiology, Laranjeiras, Brazil 2018-12-30
NCT03144011 Acute Kidney Injury in Children After Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT03144011 Completed Meshalkin Research Institute of Pathology of Circulation 2018-10-01
NCT03143348 Prognostic Markers of Inflammation in Infants Undergoing Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT03143348 Completed University of Oklahoma 2019-04-15
NCT03063801 Study on the Transfusional Management of the Patients With Congenital Heart Disease Carried Out in Adulthood. https://ClinicalTrials.gov/show/NCT03063801 Completed Brugmann University Hospital 2017-06-01
NCT03047343 Evolution of Two Cohorts of Children (Univentricular and Bi-ventricular Heart) After Strapping of the Pulmonary Artery https://ClinicalTrials.gov/show/NCT03047343 Completed Brugmann University Hospital 2018-05-29
NCT02981004 PAR I - Patient-to-Annulus Relation I https://ClinicalTrials.gov/show/NCT02981004 Completed Abbott Medical Devices 2017-12-18
NCT02970071 The Application Value of STIC in the Diagnosis of Fetal Complex Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02970071 Recruiting Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 2018-12-31
NCT02914392 Study on the Relationship Between Maternal Exposure to Environmental Factors and Fetal Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02914392 Recruiting Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 2018-07-31
NCT02897323 Northwest Adult Congenital Heart Disease Observatory https://ClinicalTrials.gov/show/NCT02897323 Recruiting University Hospital, Caen 2019-10-31
NCT02814539 Brain Function in Children With Congenital Heart Disease (CHD) https://ClinicalTrials.gov/show/NCT02814539 Completed University Children’s Hospital, Zurich 2019-09-30
NCT02781545 Motor Development of Children That Have Surgery as Newborns for Complex Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02781545 Active, not recruiting Advocate Health Care 2019-06-30
NCT02712606 Accuracy of Pulse Oximeter With Hypoxemic Measurements https://ClinicalTrials.gov/show/NCT02712606 Completed Seoul National University Hospital 2017-03-31
NCT02686255 Hemoglobin Trend in Neonates and Toddlers Post Cardiac Surgery https://ClinicalTrials.gov/show/NCT02686255 Completed Rabin Medical Center 2018-05-31
NCT01656941 Genetic Determinants of Congenital Heart Disease Outcomes https://ClinicalTrials.gov/show/NCT01656941 Active, not recruiting University of Michigan 2024-12-31
NCT02498626 Mixed Venous Oxygen Saturation From Central Venous Line, Venous Side of Heart Lung Machine and the Pulmonary Artery https://ClinicalTrials.gov/show/NCT02498626 Completed Assiut University 2016-01-31
NCT02463292 Quality of Life in Young Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02463292 Completed University Children’s Hospital, Zurich 2016-05-31
NCT02443662 Colloid Osmotic Pressure in Patients With Fontan Circulation https://ClinicalTrials.gov/show/NCT02443662 Completed Oslo University Hospital 2017-12-31
NCT02433990 Risk Factors for Acquired Cardiovascular Disease in Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02433990 Completed Stanford University 2018-04-24
NCT02432079 Molecular Genetics of Heterotaxy and Related Congenital Heart Defects https://ClinicalTrials.gov/show/NCT02432079 Recruiting Indiana University 2021-06-30
NCT02417259 Near Infrared Spectroscopy in Cyanotic Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02417259 Completed KK Women’s and Children’s Hospital 2016-06-30
NCT02409706 Micronutrients in Children in Critical Care With Cardiac Conditions https://ClinicalTrials.gov/show/NCT02409706 Completed NHS Greater Glasgow and Clyde 2016-01-31
NCT02387944 Bedside Evaluation of Coagulation in Children With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02387944 Completed Centre Hospitalier Universitaire Vaudois 2017-07-06
NCT02333097 Non Syndromic Congenital Heart Defect and Array-CGH in Prenatal Diagnosis https://ClinicalTrials.gov/show/NCT02333097 Completed Rennes University Hospital 2018-08-31
NCT02326649 Noninvasive Measurement of CO Using Impedance Cardiography in Patients With CHD https://ClinicalTrials.gov/show/NCT02326649 Completed University of California, San Diego 2016-02-29
NCT02306057 Fluid Balance in Children Undergoing Fontan Surgery https://ClinicalTrials.gov/show/NCT02306057 Completed Oslo University Hospital 2017-03-31
NCT02266251 Optimizing Health Outcomes in Patients With Symptomatic Aortic Valve Disease https://ClinicalTrials.gov/show/NCT02266251 Completed Duke University 2017-04-30
NCT02260362 Observatory of Pulmonary Arterial Hypertension of Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02260362 Active, not recruiting French Cardiology Society 2021-11-30
NCT02193243 Value of 6-minute Walk Test in Grown Ups With Congenital Heart Defects (GUCH) https://ClinicalTrials.gov/show/NCT02193243 Completed Heinrich-Heine University, Duesseldorf 2014-08-31
NCT02150603 Patient-Reported Outcomes in Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02150603 Completed Universitaire Ziekenhuizen Leuven 2015-02-28
NCT02026557 Mortality Among Children With Congenital Heart Defects in Norway https://ClinicalTrials.gov/show/NCT02026557 Completed Sorlandet Hospital HF 2009-12-31
NCT02081235 Incidence, Risk Factors, and Risk Model of Acute Kidney Injury in Pediatric Patients Who Undergoing Surgery for Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02081235 Completed Samsung Medical Center 2016-02-29
NCT02064179 Assessment of the Efficacy of the First Aspirin Dose in Children Undergoing Surgery for Congenital Heart Disease (CHD) Who Require Post-operative Antiplatelet Therapy https://ClinicalTrials.gov/show/NCT02064179 Completed University of Colorado, Denver 2015-06-30
NCT01952171 The Genetic Basis of Congenital Heart Disease in Africa https://ClinicalTrials.gov/show/NCT01952171 Active, not recruiting National Institutes of Health Clinical Center (CC) 2023-09-01
NCT01849120 NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery https://ClinicalTrials.gov/show/NCT01849120 Completed Mayo Clinic 2015-09-30
NCT01845402 Chronic Kidney Disease in Teenagers With Congenital Cardiac Disease https://ClinicalTrials.gov/show/NCT01845402 Completed Assistance Publique - Hôpitaux de Paris 2015-06-19
NCT01821287 Nutritional Failure in Infants With Single Ventricle Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01821287 Completed Children’s Hospital Medical Center, Cincinnati 2013-10-31
NCT01774890 ST2, a Novel Biomarker for Cardiac Remodeling in Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01774890 Completed Hadassah Medical Organization 2015-01-31
NCT01757743 Fluid Balance During Closure of Atrial Septal Defect https://ClinicalTrials.gov/show/NCT01757743 Completed Oslo University Hospital 2017-01-31
NCT01749059 The Impact of Implementing a Universal Newborn Screening for Critical Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01749059 Completed Mednax Center for Research, Education, Quality and Safety 2016-10-31
NCT01669057 Study on Clinical Prognosis, Risk Factors and Genetic Basis of Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01669057 Completed Children’s Hospital of Fudan University NA
NCT01665261 Newborn Screening for Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01665261 Completed Children’s Hospital of Fudan University 2012-09-30
NCT01639937 Myocardial Perfusion and Scarring in Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01639937 Completed National Institutes of Health Clinical Center (CC) NA
NCT01632813 Leuven Growing Into Deficit Follow-up Study https://ClinicalTrials.gov/show/NCT01632813 Completed KU Leuven 2014-09-30
NCT01616394 Postoperative Troponin in Children With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01616394 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2014-10-31
NCT01603732 Association Between a Mother’s Exposure to “Strep Throat” and Her Baby’s Developing Heart Disease https://ClinicalTrials.gov/show/NCT01603732 Completed Washington University School of Medicine 2015-12-31
NCT01531985 Urine and Serum Biomarkers for Early Detection of Acute Kidney Injury https://ClinicalTrials.gov/show/NCT01531985 Completed Medical College of Wisconsin 2012-03-31
NCT01503307 Parenting After Infant Congenital Heart Defect Diagnosis https://ClinicalTrials.gov/show/NCT01503307 Completed Medical College of Wisconsin 2016-07-31
NCT01489475 Plasma Angiopoietin Levels in Children Following Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT01489475 Completed Yale University 2013-06-30
NCT01460316 Conotruncal Cardiac Defects and Nutrigenetic Etiopathogeny https://ClinicalTrials.gov/show/NCT01460316 Completed Central Hospital, Nancy, France 2015-05-31
NCT03348397 Contegra Versus Pulmonary Homograft for Right Ventricular Outflow Tract Reconstruction in Newborns https://ClinicalTrials.gov/show/NCT03348397 Completed Queen Fabiola Children’s University Hospital 2017-06-01
NCT01397526 Colloid Osmotic Pressure During Heart Surgery in Children https://ClinicalTrials.gov/show/NCT01397526 Completed Oslo University Hospital 2013-05-31
NCT04413071 Cardiac COVID-19 Health Care Workers https://ClinicalTrials.gov/show/NCT04413071 Completed AORTICA Group 2020-06-12
NCT04382573 Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. https://ClinicalTrials.gov/show/NCT04382573 Recruiting University Hospital, Montpellier 2020-12-01
NCT04354220 Capnography Monitoring in Ventilated Children https://ClinicalTrials.gov/show/NCT04354220 Recruiting University Children’s Hospital, Zurich 2023-12-31
NCT04336384 Impact of Covid-19 in Congenital Heart Disease https://ClinicalTrials.gov/show/NCT04336384 Recruiting University Hospital, Montpellier 2020-12-01
NCT04233775 Altered Cerebral Growth and Development in Infants With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT04233775 Recruiting University Children’s Hospital, Zurich 2023-12-31
NCT04231591 NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Patients https://ClinicalTrials.gov/show/NCT04231591 Recruiting Mayo Clinic 2020-12-31
NCT04221048 Accuracy of Risk Prediction Scores in Pregnant Women https://ClinicalTrials.gov/show/NCT04221048 Completed University Hospital, Montpellier 2019-10-01
NCT04151160 Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT04151160 Recruiting University of Colorado, Denver 2021-02-28
NCT04136379 Comparison of Home and Standard Clinic Monitoring of INR in Patients With CHD https://ClinicalTrials.gov/show/NCT04136379 Recruiting University of Ulster 2021-03-31
NCT04106479 NIRS in Congenital Heart Defects - Correlation With Echocardiography https://ClinicalTrials.gov/show/NCT04106479 Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre 2021-08-01
NCT04041557 Executive Functions in Adults With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT04041557 Completed University Children’s Hospital, Zurich 2018-09-20
NCT03990779 Echocardiography Findings and Perioperative Outcomes in Children https://ClinicalTrials.gov/show/NCT03990779 Recruiting Seoul National University Hospital 2020-12-30
NCT03971344 Impact of Serious Pediatric Illness on Parent and Sibling Health https://ClinicalTrials.gov/show/NCT03971344 Active, not recruiting Children’s Hospital of Philadelphia 2020-07-31
NCT03941015 Tissue Oxygenation During Treatment of Infant Congenital Heart Defects https://ClinicalTrials.gov/show/NCT03941015 Recruiting Beijing Anzhen Hospital 2020-07-31
NCT03931096 Quality of Life Assessment of Children With Congenital Heart Disease Aged 5 to 7 Years https://ClinicalTrials.gov/show/NCT03931096 Completed University Hospital, Montpellier 2019-12-01
NCT03917706 Development of a Quality of Life Assessment Tool for Adult Patients With a Congenital Heart Disease, Having Had Surgery During Childhood https://ClinicalTrials.gov/show/NCT03917706 Completed Brugmann University Hospital 2019-07-15
NCT03877965 Pharmacokinetics and Safety Profile of Digoxin in Infants With Single Ventricle Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03877965 Enrolling by invitation Duke University 2022-06-01
NCT03833843 Sudden Cardiac Death in Systemic Right Ventricle https://ClinicalTrials.gov/show/NCT03833843 Recruiting European Georges Pompidou Hospital 2019-09-01
NCT03737006 Coxsackie Virus in Pregnancy and Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03737006 Active, not recruiting Washington University School of Medicine 2020-12-01
NCT03678909 Cardiac Biomarkers in Patients With Single Ventricle Physiology https://ClinicalTrials.gov/show/NCT03678909 Recruiting Baylor College of Medicine 2020-03-30
NCT03642405 Drug-induced Repolarization ECG Changes https://ClinicalTrials.gov/show/NCT03642405 Active, not recruiting Copenhagen University Hospital at Herlev 2019-09-03
NCT03626480 Peri-operative Nutrition in Infants With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03626480 Recruiting Guangzhou Medical University 2028-09-01
NCT03588312 Long Term Results in Hypoplastic Aortic Arch Repair in Neonates Using a Glutaraldehyde Treated Autologous Pericardial Patch https://ClinicalTrials.gov/show/NCT03588312 Recruiting Queen Fabiola Children’s University Hospital 2018-09-01
NCT03564522 Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary Hypertension https://ClinicalTrials.gov/show/NCT03564522 Recruiting University of Michigan 2021-02-28
NCT03487302 White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study https://ClinicalTrials.gov/show/NCT03487302 Recruiting IRCCS Policlinico S. Donato 2020-12-31
NCT03440697 Pathogenetic Basis of Aortopathy and Aortic Valve Disease https://ClinicalTrials.gov/show/NCT03440697 Recruiting Indiana University 2025-12-31
NCT03411512 Congenital Heart Defects and NIRS https://ClinicalTrials.gov/show/NCT03411512 Completed University Medical Centre Ljubljana 2014-04-30
NCT01212289 Use of ROTEM® in Pediatric Cardiac Surgical Patients https://ClinicalTrials.gov/show/NCT01212289 Completed Weill Medical College of Cornell University 2014-02-28
NCT01202916 Quality of Life Among Children With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01202916 Completed University Hospital, Montpellier 2011-09-30
NCT01201486 Use of Color Doppler in Routine Examination of Fetal Heart in Second Trimester https://ClinicalTrials.gov/show/NCT01201486 Completed Helse Stavanger HF 2009-08-31
NCT01196182 Congenital Heart Disease GEnetic NEtwork Study (CHD GENES) https://ClinicalTrials.gov/show/NCT01196182 Recruiting Children’s Hospital Medical Center, Cincinnati 2022-12-31
NCT01194362 A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease https://ClinicalTrials.gov/show/NCT01194362 Active, not recruiting Baylor Research Institute 2020-12-31
NCT01192048 Genetics of Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01192048 Recruiting Nationwide Children’s Hospital 2025-12-31
NCT03871881 Impact of Congenital Heart Disease on Neurodevelopmental Outcome https://ClinicalTrials.gov/show/NCT03871881 Recruiting University of Aarhus 2020-07-01
NCT01126372 Prediction of Feeding Problems in Prostaglandin-dependent Prematurely Born Infants With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01126372 Completed University of Utah 2013-06-30
NCT01045356 Pharmacokinetics of Tranexamic Acid (TXA) in Children Undergoing Repair of Congenital Heart Defects Utilizing Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT01045356 Completed Boston Children’s Hospital 2014-11-30
NCT00932633 Magnetic Resonance Imaging (MRI) to Evaluate Brain Injury in Congenital Heart Disease https://ClinicalTrials.gov/show/NCT00932633 Completed Emory University 2016-01-31
NCT00883922 Central Venous Saturation (ScvO2) Monitoring in Pediatric Patients Undergoing Cardiac Surgery https://ClinicalTrials.gov/show/NCT00883922 Completed University of California, Los Angeles 2010-03-31
NCT04093011 Perioperative Outcome of Congenital Heart Disease Surgery in Childhood https://ClinicalTrials.gov/show/NCT04093011 Recruiting Nanjing Medical University 2019-12-31
NCT01567579 An Evaluation of Routine Developmental Follow-Up in Infants and Children With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT01567579 Recruiting Medical College of Wisconsin 2025-12-31
NCT02737644 Peri-conception Key Nutritional Factors and Congenital Heart Disease https://ClinicalTrials.gov/show/NCT02737644 Recruiting Children’s Hospital of Fudan University 2020-11-30
NCT03912025 The Relationship Between Having a Positive Mindset and Exercise Capacity in Patients With Congenital Heart Disease https://ClinicalTrials.gov/show/NCT03912025 Recruiting Boston Children’s Hospital 2020-12-31
NCT00713635 Prenatal Effects of Congenital Heart Disease (CHD) on Neurodevelopmental Outcome https://ClinicalTrials.gov/show/NCT00713635 Completed Columbia University 2014-11-30
NCT00608556 Dyskinesia, Heterotaxy and Congenital Heart Disease https://ClinicalTrials.gov/show/NCT00608556 Completed National Institutes of Health Clinical Center (CC) NA
NCT00497705 Genes Causing Ebstein’s Anomaly https://ClinicalTrials.gov/show/NCT00497705 Completed National Institutes of Health Clinical Center (CC) 2009-07-07
NCT00397514 Assessing the Hemodynamic Benefits of Cardiac Resynchronization Therapy in Children Following Open-Heart Surgery https://ClinicalTrials.gov/show/NCT00397514 Completed University of British Columbia 2009-11-30
NCT00368732 Genetic and Nutritional Causes of Heart Birth Defects https://ClinicalTrials.gov/show/NCT00368732 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00303511 Pacemaker Therapy in Adults With Congenital Heart Defects https://ClinicalTrials.gov/show/NCT00303511 Completed Emory University 2006-08-31
NCT00266201 Right Ventricular Failure in Congenital Heart Defects https://ClinicalTrials.gov/show/NCT00266201 Completed Competence Network for Congenital Heart Defects NA
NCT00165945 4-D Visualization Using Magnetic Resonance Imaging (MRI) in the Congenital Heart Disease Population https://ClinicalTrials.gov/show/NCT00165945 Completed Emory University 2009-03-31
NCT00132782 Relationship Between Functional Health Status and Ventricular Performance After Fontan–Pediatric Heart Network https://ClinicalTrials.gov/show/NCT00132782 Completed HealthCore-NERI 2004-04-30
NCT00027196 Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease https://ClinicalTrials.gov/show/NCT00027196 Completed National Institutes of Health Clinical Center (CC) NA
NCT00446927 SPY Imaging System: Its Role in Pediatric Cardiac Surgery https://ClinicalTrials.gov/show/NCT00446927 Completed Emory University 2012-01-31
NCT00005546 Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular Disease https://ClinicalTrials.gov/show/NCT00005546 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005323 Epidemiology of Persistent Pulmonary Hypertension of the Newborn - SCOR in Lung Biology and Diseases in Infants and Children https://ClinicalTrials.gov/show/NCT00005323 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005322 Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease https://ClinicalTrials.gov/show/NCT00005322 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005258 Family Study of Congenital Cardiovascular Malformations https://ClinicalTrials.gov/show/NCT00005258 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005190 Reproduction and Survival After Cardiac Defect Repair https://ClinicalTrials.gov/show/NCT00005190 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00005153 Etiologic Risk Factors of Cardiovascular Malformations https://ClinicalTrials.gov/show/NCT00005153 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000107 Body Water Content in Cyanotic Congenital Heart Disease https://ClinicalTrials.gov/show/NCT00000107 Completed National Center for Research Resources (NCRR) NA
NCT00004361 Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects https://ClinicalTrials.gov/show/NCT00004361 Completed Office of Rare Diseases (ORD) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03227848 eMurmur ID - Clinical Performance Evaluation https://ClinicalTrials.gov/show/NCT03227848 Completed CSD Labs GmbH 2018-04-24
NCT03119155 Improvement on Diagnosis of Fetal Congenital Heart Disease Based on Multi-center Collaboration in China https://ClinicalTrials.gov/show/NCT03119155 Recruiting Beijing Anzhen Hospital 2020-12-31
NCT02968264 Tetralogy of Fallot for Life https://ClinicalTrials.gov/show/NCT02968264 Active, not recruiting Population Health Research Institute 2021-05-01
NCT02806310 Podocan and Wnt Pathway in the Development of Aortopathy in Bicuspid Valve Disease https://ClinicalTrials.gov/show/NCT02806310 Active, not recruiting Bassett Healthcare 2020-06-30
NCT02618707 Lactate Levels During Cardiopulmonary Bypass in Pediatric Patients https://ClinicalTrials.gov/show/NCT02618707 Completed Assiut University 2016-03-31
NCT02258724 Swiss National Registry of Grown up Congenital Heart Disease Patients https://ClinicalTrials.gov/show/NCT02258724 Recruiting University Hospital, Basel, Switzerland 2033-12-31
NCT04202796 Catheter Ablation in Congenital Heart Disease: French National Prospective Registry https://ClinicalTrials.gov/show/NCT04202796 Recruiting Paris Cardiovascular Research Center (Inserm U970) 2021-12-31
NCT04141605 Global Utilization And Registry Database for Improved heArt preservatioN https://ClinicalTrials.gov/show/NCT04141605 Enrolling by invitation Paragonix Technologies 2022-12-31
NCT04130243 Biomarkers in Pediatric Congenital Heart Disease and PAH https://ClinicalTrials.gov/show/NCT04130243 Recruiting University Medical Center Groningen 2021-12-01
NCT03957512 Livet Skal Leves (A Life to Live) https://ClinicalTrials.gov/show/NCT03957512 Completed Oslo University Hospital 2017-12-31